Preview Mode Links will not work in preview mode

Huberman Lab

Visit the official Huberman Lab website at

Jul 26, 2021

This episode I describe how the organs of the body influence the function and health of our brain and how our brain controls our bodily organs. The conscious awareness of this brain-body dialogue is called interoception. I describe how two factors- mechanical forces (e.g., pressure, pain, volume, etc.) and chemical factors (e.g., gut acidity, microbiome diversity, etc.) combine to influence our moods, control inflammation, immune system, recovery from injury and more. I explain how specific actions of our lungs, heart, spleen, and diaphragm, control our brain via the vagus nerve and other neural pathways. I describe 11 science-supported protocols for enhancing brain-body health and the logic behind them.


Thank you to our sponsors:


Our Patreon page:


Supplements from Thorne:







  • 00:00:00 Your Sense of Self: Interoception
  • 00:01:25 Protocol 1: Fermented Foods, Not Fiber, to Reduce Inflammation 
  • 00:03:30 Attributions
  • 00:08:22 Main Drivers of Feelings & Performance
  • 00:11:45 Brain-Body: A Mechanical & Chemical Dialogue 
  • 00:17:50 LDB (Lung-Diaphragm-Brain) Dialogue  
  • 00:21:00 Protocols 2, 3, 4: Control Heart Rate With Breathing
  • 00:29:08 Sensing Lung Pressure: Piezo Receptors
  • 00:30:54 Carbon Dioxide, From Air to Blood
  • 00:34:02 Protocol 5: Alert While Calm
  • 00:40:50 Baroreceptors: Hering-Breuer Reflex
  • 00:42:47 Gut Volume & The Desire to Open Your Mouth 
  • 00:48:18 Protocol 6: Enhancing Gut-To-Brain Communication, Fasting 
  • 00:51:50 Intestines, Fatty Acids, Amino Acids & Sugar
  • 00:57:00 Protocol 7: Reducing Sugar Cravings with Specific Amino Acid Nutrients 
  • 00:58:58 Gut Acidity (Is Good)
  • 01:02:20: Improving Nasal Microbiome 
  • 01:04:13 Inflammation & Microbiome: Fiber vs. Fermented 
  • 01:11:15 Protocol 8: Reducing Inflammation & Enhancing Brain Function w/Fermented Foods
  • 01:13:10 Leaking Guts, Auto-Immune function & Glutamine
  • 01:15:50 Gut Acidity: HCl (hydrochloric acid), Pepsin
  • 01:18:30 Probiotics & Brain Fog
  • 01:21:45 Nausea: Happens in Your Brain; Area Postrema
  • 01:28:25 Protocol 9: Reducing Nausea: Ginger, Peppermint, CBD, etc.
  • 01:30:40 Fever: Triggers and Control Knobs: OVLT
  • 01:37:00 Protocol 10: Cooling the Blood Properly
  • 01:38:53 Sensing Feelings, Vagus Nerve, Stress
  • 01:41:50 Mental Emotions Reflect Bodily Conditions
  • 01:45:00 Sensing Other People’s Emotions via the Body
  • 01:46:00 Protocol 11: Increasing Interoception, Sensing Heartbeat 
  • 01:50:40 Conclusions & Resources


Please note that The Huberman Lab Podcast is distinct from Dr. Huberman's teaching and research roles at Stanford University School of Medicine. The information provided in this show is not medical advice, nor should it be taken or applied as a replacement for medical advice. The Huberman Lab Podcast, its employees, guests and affiliates assume no liability for the application of the information discussed.


Title Card Photo Credit: Mike Blabac -